2021 PACES expert consensus statement on the indications and management of cardiovascular implantable electronic devices in pediatric patients

Maully J. Shah, Michael J. Silka, Jennifer N.Avari Silva, Seshadri Balaji, Cheyenne M. Beach, Monica N. Benjamin, Charles I. Berul, Bryan Cannon, Frank Cecchin, Mitchell I. Cohen, Aarti S. Dalal, Brynn E. Dechert, Anne Foster, Roman Gebauer, M. Cecilia Gonzalez Corcia, Prince J. Kannankeril, Peter P. Karpawich, Jeffery J. Kim, Mani Ram Krishna, Peter KubušMartin J. Lapage, Douglas Y. Mah, Lindsey Malloy-Walton, Aya Miyazaki, Kara S. Motonaga, Mary C. Niu, Melissa Olen, Thomas Paul, Eric Rosenthal, Elizabeth V. Saarel, Massimo Stefano Silvetti, Elizabeth A. Stephenson, Reina B. Tan, John Triedman, Nicholas H. Von Bergen, Philip L. Wackel

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


In view of the increasing complexity of both cardiovascular implantable electronic devices (CIEDs) and patients in the current era, practice guidelines, by necessity, have become increasingly specific. This document is an expert consensus statement that has been developed to update and further delineate indications and management of CIEDs in pediatric patients, defined as ≤21 years of age, and is intended to focus primarily on the indications for CIEDs in the setting of specific disease categories. The document also highlights variations between previously published adult and pediatric CIED recommendations and provides rationale for underlying important differences. The document addresses some of the deterrents to CIED access in low- and middle-income countries and strategies to circumvent them. The document sections were divided up and drafted by the writing committee members according to their expertise. The recommendations represent the consensus opinion of the entire writing committee, graded by class of recommendation and level of evidence. Several questions addressed in this document either do not lend themselves to clinical trials or are rare disease entities, and in these instances recommendations are based on consensus expert opinion. Furthermore, specific recommendations, even when supported by substantial data, do not replace the need for clinical judgment and patient-specific decision-making. The recommendations were opened for public comment to Pediatric and Congenital Electrophysiology Society (PACES) members and underwent external review by the scientific and clinical document committee of the Heart Rhythm Society (HRS), the science advisory and coordinating committee of the American Heart Association (AHA), the American College of Cardiology (ACC), and the Association for European Paediatric and Congenital Cardiology (AEPC). The document received endorsement by all the collaborators and the Asia Pacific Heart Rhythm Society (APHRS), the Indian Heart Rhythm Society (IHRS), and the Latin American Heart Rhythm Society (LAHRS). This document is expected to provide support for clinicians and patients to allow for appropriate CIED use, appropriate CIED management, and appropriate CIED follow-up in pediatric patients.

Original languageEnglish
Pages (from-to)1738-1769
Number of pages32
JournalCardiology in the Young
Issue number11
StatePublished - Nov 2 2021
Externally publishedYes


  • Bradycardia
  • Brugada syndrome
  • ECG
  • Long QT syndrome
  • MR imaging
  • ambulatory ECG monitoring
  • antiarrhythmic drug therapy
  • antitachycardia pacing
  • arrhythmogenic cardiomyopathy
  • arrhythmogenic right ventricular cardiomyopathy
  • asystole
  • atrioventricular block
  • cardiac channelopathies
  • cardiac transplantation
  • cardiomyopathy
  • cardiovascular implantable electronic devices
  • catecholaminergic polymorphic ventricular tachycardia
  • children
  • congenital heart disease
  • coronary artery compression
  • echocardiography
  • endocardial lead
  • epicardial lead
  • expert consensus statement
  • genetic arrhythmias
  • heart block
  • heart failure
  • hypertrophic cardiomyopathy
  • implantable cardioverter defibrillator
  • insertable cardiac monitor
  • lead extraction
  • lead removal
  • low- and middle-income countries
  • neuromuscular disease
  • pacemaker
  • pediatrics
  • postoperative
  • remote monitoring
  • shared decision-making
  • sick sinus syndrome
  • sports and physical activity
  • sudden cardiac arrest
  • sudden cardiac death
  • syncope
  • transvenous
  • ventricular fibrillation
  • ventricular tachycardia


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