A comparative biocompatibility analysis of ternary nitinol alloys

Waseem Haider, Norman Munroe, Chandan Pulletikurthi, Puneet K.Singh Gill, Sushma Amruthaluri

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

Nitinol alloys are rapidly being utilized as the material of choice in a variety of applications in the medical industry. It has been used for self-expanding stents, graft support systems, and various other devices for minimally invasive interventional and endoscopic procedures. However, the biocompatibility of this alloy remains a concern to many practitioners in the industry due to nickel sensitivity experienced by many patients. In recent times, several new Nitinol alloys have been introduced with the addition of a ternary element. Nevertheless, there is still a dearth of information concerning the biocompatibility and corrosion resistance of these alloys. This study compared the biocompatibility of two ternary Nitinol alloys prepared by powder metallurgy (PM) and arc melting (AM) and critically assessed the influence of the ternary element. ASTM F 2129-08 cyclic polarization in vitro corrosion tests were conducted to evaluate the corrosion resistance in phosphate buffered saline (PBS). The growth of endothelial cells on NiTi was examined using optical microscopy.

Original languageEnglish
Pages (from-to)760-764
Number of pages5
JournalJournal of Materials Engineering and Performance
Volume18
Issue number5-6
DOIs
StatePublished - Aug 2009

Keywords

  • Biocompatibility
  • Endothelial cells
  • Nitinol
  • Sintering
  • Stents

Fingerprint

Dive into the research topics of 'A comparative biocompatibility analysis of ternary nitinol alloys'. Together they form a unique fingerprint.

Cite this