A comparison of generalized Poisson distribution for modeling chromosome aberrations

Carl M.S. Lee, Felix Famoye

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Various models have been developed for modeling the distribution of chromosome aberrations in the literature (e. g. CONSUL, 1989). Generalized Poisson distribution is among the popular ones. The parameters of this distribution provide meaningful interpretation of the induction mechanism of the chromosome aberrations. In this article, we apply several estimation methods to estimate the generalized Poisson parameters for fitting the number of chromosome aberrations under different dosages of radiations. The methods compared are moment, maximum likelihood, minimum chi-square, weighted discrepancy and empirically weighted rates of change. Our study suggests that the empirically weighted rates of change method results in smallest Mean Square Error and Mean Absolute Error for most dosages of radiations. The data used for this comparison are from JANARDAN and SCHAEFFER (1977).

Original languageEnglish
Pages (from-to)299-313
Number of pages15
JournalBiometrical Journal
Issue number3
StatePublished - 1996


  • Discrepancy
  • Empirically weighted rates of change
  • Estimation
  • Minimum chi-square
  • Moment


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