A Multidisciplinary Approach to Determine Heparin Dosing in Pediatric Vascular Devices

Charlotta Marshall, Kathrina Boldt-MacDonald, Richard McLenon, Elizabeth Rennie, May Faraon, Sandra Conoff, Jennifer Lesnek, Cristie Becker, Roland Chu

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


In the health care community, nurses are important agents of change and vehicles for improvements in clinical practice and policy. Pediatric nurses empowered with the tools of evidence-based practice and clinical expertise collaborated in 2007 with other health care professionals to make changes in clinical practice for pediatric patients with vascular access devices (VADs). Nurses recognized that there was a need for a change in the heparinization policy for children with short- and long-term VADs. Data were methodically collected over a 1-year period on 500 VAD. Data collection demonstrated a range of VAD volumes that did not exceed 2 mL. The group analysis of the results gave support for changes in the volumes needed for heparinization. Establishment of appropriate heparin dosing based on scientific data led to a decrease in heparin used to maintain pediatric VAD patency and aided in lowering the risk of side effects in patients.

Original languageEnglish
Pages (from-to)53-57
Number of pages5
JournalJournal of Pediatric Oncology Nursing
Issue number1
StatePublished - Jan 2011


  • Central vascular access devices (CVADS)
  • Evidence-based practice
  • Nurses as change agents


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