Acute myeloid leukaemia with t(8;16)(p11;p13) in a child after intrauterine X-ray exposure

Süreyya Savaşan, Anwar N. Mohamed, David R. Lucas, Michael C. Dugan, James R. Ryan, Yaddanapudi Ravindranath

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9 Scopus citations

Abstract

We describe t(8;16)(p11;p13) acute myeloid leukaemia (AML-M4) in a 12-year-old white male with a history of prenatal X-ray exposure. He had skin and bone involvement and some of the leukaemic blasts showed haemophagocytosis; characteristic features seen in t(8;16) AML. 20% of the reported cases of t(8;16)(p11;p13) AML are therapy related and this case further supports the possible role of the ionizing radiation in the development of this disorder.

Original languageEnglish
Pages (from-to)702-704
Number of pages3
JournalBritish Journal of Haematology
Volume94
Issue number4
DOIs
StatePublished - 1996

Keywords

  • AML-M4
  • Prenatal X-ray exposure
  • t(8;16)

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