TY - JOUR
T1 - Acute myocardial ischemia in association with acute respiratory acidosis in hemoglobin SC disease
T2 - A case report
AU - Gayanilo, Marjorie
AU - Nares, Michael
AU - Alvarez, Ofelia
AU - Swaminathan, Sethuraman
PY - 2014/3
Y1 - 2014/3
N2 - Hemoglobin SC (HbSC) disease is the second most common inherited disorder of hemoglobin, in which there is a coinheritance of mutated b globin genes resulting in hemoglobin S and hemoglobin C.1 HbSC is less severe than the homozygous HbSS disease but some complications can be equally severe. Acute myocardial ischemia and infarction have been reported on rare occasions in children with HbSS disease. However, this complication is not reported in children with HbSC disease. We report one such case of acute myocardial ischemia in an adolescent with HbSC disease, in association with acute chest syndrome.
AB - Hemoglobin SC (HbSC) disease is the second most common inherited disorder of hemoglobin, in which there is a coinheritance of mutated b globin genes resulting in hemoglobin S and hemoglobin C.1 HbSC is less severe than the homozygous HbSS disease but some complications can be equally severe. Acute myocardial ischemia and infarction have been reported on rare occasions in children with HbSS disease. However, this complication is not reported in children with HbSC disease. We report one such case of acute myocardial ischemia in an adolescent with HbSC disease, in association with acute chest syndrome.
KW - hemoglobin SC
KW - myocardial ischemia
KW - sickle cell crisis
UR - http://www.scopus.com/inward/record.url?scp=84896728408&partnerID=8YFLogxK
U2 - 10.1097/01.mph.0000438028.87141.8c
DO - 10.1097/01.mph.0000438028.87141.8c
M3 - Article
C2 - 24322498
AN - SCOPUS:84896728408
SN - 1077-4114
VL - 36
SP - e97-e99
JO - Journal of Pediatric Hematology/Oncology
JF - Journal of Pediatric Hematology/Oncology
IS - 2
ER -