Advances in Tourette Syndrome. Diagnoses and Treatment.

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Tourette syndrome (TS) is a childhood-onset neurodevelopmental disorder characterized by multiple motor tics and at least one vocal or phonic tic, and often one or more comorbid psychiatric disorders. Premonitory sensory urges before tic execution and desire for "just-right" perception are central features. The pathophysiology involves cortico-striato-thalamo-cortical circuits and possibly dopaminergic system. TS is considered a genetic disorder but the genetics is complex and likely involves rare mutations, common variants, and environmental and epigenetic factors. Treatment is multimodal and includes education and reassurance, behavioral interventions, pharmacologic, and rarely, surgical interventions.

Original languageEnglish
Pages (from-to)687-701
Number of pages15
JournalPediatric Clinics of North America
Issue number3
StatePublished - Jun 1 2015


  • ADHD
  • OCD
  • Tics
  • Tourette


Dive into the research topics of 'Advances in Tourette Syndrome. Diagnoses and Treatment.'. Together they form a unique fingerprint.

Cite this