TY - JOUR
T1 - Aerosolized vaccine as an unexpected source of false-positive Bordetella pertussis PCR results
AU - Salimnia, Hossein
AU - Lephart, Paul R.
AU - Asmar, Basim I.
AU - Prebelich, Dawn
AU - Paulson, Erin
AU - Fairfax, Marilynn R.
PY - 2012/2
Y1 - 2012/2
N2 - When 13 of 13 nasal wash specimens from a single pediatrician's office tested positive for low quantities of Bordetella pertussis DNA, we suspected prelaboratory contamination. Investigation revealed that Pentacel and Adacel vaccines contain high copy numbers of B. pertussis DNA, which can be aerosolized, causing false-positive B. pertussis PCR results.
AB - When 13 of 13 nasal wash specimens from a single pediatrician's office tested positive for low quantities of Bordetella pertussis DNA, we suspected prelaboratory contamination. Investigation revealed that Pentacel and Adacel vaccines contain high copy numbers of B. pertussis DNA, which can be aerosolized, causing false-positive B. pertussis PCR results.
UR - http://www.scopus.com/inward/record.url?scp=84856149642&partnerID=8YFLogxK
U2 - 10.1128/JCM.01250-11
DO - 10.1128/JCM.01250-11
M3 - Article
C2 - 22162551
AN - SCOPUS:84856149642
SN - 0095-1137
VL - 50
SP - 472
EP - 474
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
IS - 2
ER -