Altered in vitro immune response to hypoxia-treated normal peritoneal fibroblasts

Zeynep Alpay; Melike Özgönenel; Süreyya Savaşan; Steven Buck; Ghassan M. Saed; Michael P. Diamond

doi:10.1016/j.fertnstert.2006.07.1495

Altered in vitro immune response to hypoxia-treated normal peritoneal fibroblasts

Zeynep Alpay, Melike Özgönenel, Süreyya Savaşan, Steven Buck, Ghassan M. Saed, Michael P. Diamond

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Hypoxia treatment of normal peritoneal fibroblasts results in alterations that are characteristic for fibroblasts obtained from postoperative peritoneal adhesion tissue. In this study, we have shown that hypoxia treatment enhances normal peritoneal fibroblast elimination by lymphokine-activated killer cells to the level of adhesion tissue fibroblasts, suggesting a pivotal role of hypoxia in the adhesion development.

Original language	English
Pages (from-to)	426-429
Number of pages	4
Journal	Fertility and Sterility
Volume	87
Issue number	2
DOIs	https://doi.org/10.1016/j.fertnstert.2006.07.1495
State	Published - Feb 2007

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10.1016/j.fertnstert.2006.07.1495

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title = "Altered in vitro immune response to hypoxia-treated normal peritoneal fibroblasts",

abstract = "Hypoxia treatment of normal peritoneal fibroblasts results in alterations that are characteristic for fibroblasts obtained from postoperative peritoneal adhesion tissue. In this study, we have shown that hypoxia treatment enhances normal peritoneal fibroblast elimination by lymphokine-activated killer cells to the level of adhesion tissue fibroblasts, suggesting a pivotal role of hypoxia in the adhesion development.",

author = "Zeynep Alpay and Melike {\"O}zg{\"o}nenel and S{\"u}reyya Sava{\c s}an and Steven Buck and Saed, {Ghassan M.} and Diamond, {Michael P.}",

note = "Funding Information: Partially supported by Children{\textquoteright}s Research Center of Michigan. ",

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AU - Alpay, Zeynep

AU - Özgönenel, Melike

AU - Savaşan, Süreyya

AU - Buck, Steven

AU - Saed, Ghassan M.

AU - Diamond, Michael P.

N1 - Funding Information: Partially supported by Children’s Research Center of Michigan.

PY - 2007/2

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N2 - Hypoxia treatment of normal peritoneal fibroblasts results in alterations that are characteristic for fibroblasts obtained from postoperative peritoneal adhesion tissue. In this study, we have shown that hypoxia treatment enhances normal peritoneal fibroblast elimination by lymphokine-activated killer cells to the level of adhesion tissue fibroblasts, suggesting a pivotal role of hypoxia in the adhesion development.

AB - Hypoxia treatment of normal peritoneal fibroblasts results in alterations that are characteristic for fibroblasts obtained from postoperative peritoneal adhesion tissue. In this study, we have shown that hypoxia treatment enhances normal peritoneal fibroblast elimination by lymphokine-activated killer cells to the level of adhesion tissue fibroblasts, suggesting a pivotal role of hypoxia in the adhesion development.

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U2 - 10.1016/j.fertnstert.2006.07.1495

DO - 10.1016/j.fertnstert.2006.07.1495

M3 - Article

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AN - SCOPUS:33846647085

SN - 0015-0282

VL - 87

SP - 426

EP - 429

JO - Fertility and Sterility

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ER -

Altered in vitro immune response to hypoxia-treated normal peritoneal fibroblasts

Abstract

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