Anthracyclines and related substances. 4. A novel regio- and stereoselective total synthesis of 7-epidaunomycinone and daunomycinone.

S. David Kimball, K. S. Kim, Dillip K. Mohanty, Ermes Vanotti, Francis Johnson

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Daunomycinone 2a has been synthesized by a novel regio- and stereoselective route that establishes the tetracyclic framework and the C-7 oxygen in naphthacenol 5c via a double Friedel-Crafts acylation.

Original languageEnglish
Pages (from-to)3871-3874
Number of pages4
JournalTetrahedron Letters
Volume23
Issue number38
DOIs
StatePublished - 1982

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