Arrhythmias after astemizole overdose

Sabrina M. Heidemann; Ashok P. Sarnaik

doi:10.1097/00006565-199604000-00009

Arrhythmias after astemizole overdose

Sabrina M. Heidemann, Ashok P. Sarnaik

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Astemizole, a relatively new H1 blocker, has been reported to cause ventricular arrhythmias in the poisoned patient. We present two cases of astemizole poisoning, one with asystole followed by ventricular fibrillation occurring 11 hours after ingestion treated with defibrillation and one with an isolated finding of a prolonged corrected QT interval. Electrocardiogram monitoring to detect conduction defects can identify patients at risk of developing life-threatening arrhythmias.

Original language	English
Pages (from-to)	102-104
Number of pages	3
Journal	Pediatric Emergency Care
Volume	12
Issue number	2
DOIs	https://doi.org/10.1097/00006565-199604000-00009
State	Published - Apr 1996

Keywords

Astemizole
arrhythmias
poisoning
toxicity

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10.1097/00006565-199604000-00009

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title = "Arrhythmias after astemizole overdose",

abstract = "Astemizole, a relatively new H1 blocker, has been reported to cause ventricular arrhythmias in the poisoned patient. We present two cases of astemizole poisoning, one with asystole followed by ventricular fibrillation occurring 11 hours after ingestion treated with defibrillation and one with an isolated finding of a prolonged corrected QT interval. Electrocardiogram monitoring to detect conduction defects can identify patients at risk of developing life-threatening arrhythmias.",

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AB - Astemizole, a relatively new H1 blocker, has been reported to cause ventricular arrhythmias in the poisoned patient. We present two cases of astemizole poisoning, one with asystole followed by ventricular fibrillation occurring 11 hours after ingestion treated with defibrillation and one with an isolated finding of a prolonged corrected QT interval. Electrocardiogram monitoring to detect conduction defects can identify patients at risk of developing life-threatening arrhythmias.

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KW - poisoning

KW - toxicity

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Arrhythmias after astemizole overdose

Abstract

Keywords

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