TY - JOUR
T1 - Biodegradable Mg/HA/TiO 2 nanocomposites coated with MgO and Si/MgO for orthopedic applications
T2 - A study on the corrosion, surface characterization, and biocompatability
AU - Khalajabadi, Shahrouz Zamani
AU - Abu, Aminudin Bin Haji
AU - Ahmad, Norhayati
AU - Kadir, Mohammed Rafiq Abdul
AU - Ismail, Ahmad Fauzi
AU - Nasiri, Rozita
AU - Haider, Waseem
AU - Redzuan, Norizah Bt Hj
N1 - Publisher Copyright:
© 2017 by the authors.
PY - 2017/10/1
Y1 - 2017/10/1
N2 - In the field of orthopedics, magnesium (Mg) and magnesium-based composites as biodegradable materials have attracted fundamental research. However, the medical applications of magnesium implants have been restricted owing to their poor corrosion resistance, especially in the physiological environment. To improve the corrosion resistance of Mg/HA/TiO 2 nanocomposites, monolayer MgO and double-layer Si/MgO coatings were fabricated layer-by-layer on the surface of a nanocomposite using a powder metallurgy route. Then, coating thickness, surface morphology, and chemical composition were determined, and the corrosion behavior of the uncoated and coated samples was evaluated. Field-emission scanning electron microscopy (FE-SEM) micrographs show that an inner MgO layer with a porous microstructure and thickness of around 34 μm is generated on the Mg/HA/TiO 2 nanocomposite substrate, and that the outer Si layer thickness is obtained at around 23 μm for the double-layered coated sample. Electrochemical corrosion tests and immersion corrosion tests were carried out on the uncoated and coated samples and the Si/MgO-coated nanocomposite showed significantly improved corrosion resistance compared with uncoated Mg/HA/TiO 2 in simulated body fluid (SBF). Corrosion products comprising Mg(OH)2, HA, Ca 3 (PO 4 ) 2 , and amorphous CaP components were precipitated on the immersed samples. Improved cytocompatibility was observed with coating as the cell viability ranged from 73% in uncoated to 88% for Si/MgO-coated Mg/HA/TiO 2 nanocomposite after nine days of incubation.
AB - In the field of orthopedics, magnesium (Mg) and magnesium-based composites as biodegradable materials have attracted fundamental research. However, the medical applications of magnesium implants have been restricted owing to their poor corrosion resistance, especially in the physiological environment. To improve the corrosion resistance of Mg/HA/TiO 2 nanocomposites, monolayer MgO and double-layer Si/MgO coatings were fabricated layer-by-layer on the surface of a nanocomposite using a powder metallurgy route. Then, coating thickness, surface morphology, and chemical composition were determined, and the corrosion behavior of the uncoated and coated samples was evaluated. Field-emission scanning electron microscopy (FE-SEM) micrographs show that an inner MgO layer with a porous microstructure and thickness of around 34 μm is generated on the Mg/HA/TiO 2 nanocomposite substrate, and that the outer Si layer thickness is obtained at around 23 μm for the double-layered coated sample. Electrochemical corrosion tests and immersion corrosion tests were carried out on the uncoated and coated samples and the Si/MgO-coated nanocomposite showed significantly improved corrosion resistance compared with uncoated Mg/HA/TiO 2 in simulated body fluid (SBF). Corrosion products comprising Mg(OH)2, HA, Ca 3 (PO 4 ) 2 , and amorphous CaP components were precipitated on the immersed samples. Improved cytocompatibility was observed with coating as the cell viability ranged from 73% in uncoated to 88% for Si/MgO-coated Mg/HA/TiO 2 nanocomposite after nine days of incubation.
KW - Biodegradation behavior
KW - Corrosion products
KW - Cytocompatibility
KW - Mg/HA/TiO nanocomposite
KW - Si/MgO
UR - http://www.scopus.com/inward/record.url?scp=85044508069&partnerID=8YFLogxK
U2 - 10.3390/coatings7100154
DO - 10.3390/coatings7100154
M3 - Article
AN - SCOPUS:85044508069
SN - 2079-6412
VL - 7
JO - Coatings
JF - Coatings
IS - 10
M1 - 154
ER -