CD93: Recent advances and implications in disease

Mallary C. Greenlee-Wacker, Manuel D. Galvan, Suzanne S. Bohlson

Research output: Contribution to journalReview articlepeer-review

27 Scopus citations

Abstract

While it has been known for some time that CD93 regulates several processes involved in innate immunity and inflammation including phagocytosis and adhesion, the function of CD93 in disease progression is only now being elucidated. Recent in vivo studies in mice, and genome wide studies in mice and humans, have provided clues about its molecular function. Following a comprehensive review of CD93 expression patterns, this review will focus on recent findings over the last three years that address the putative function of CD93 in inflammation and innate immunity.

Original languageEnglish
Pages (from-to)411-420
Number of pages10
JournalCurrent Drug Targets
Volume13
Issue number3
DOIs
StatePublished - Mar 2012

Keywords

  • AA4.1
  • Adhesion
  • CD93
  • Group XIV
  • Inflammation
  • Innate immunity

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