Childhood B-Cell Acute Lymphoblastic Leukemia Following SARS CoV-2 Infection: A Potential Second "Hit" in Leukemogenesis

Yogindra Persaud, Mark Shamoun, Meera Chitlur, Kyle J. Des Rosier, Jeffrey W. Taub

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The Coronavirus Disease 2019 (COVID-19) pandemic has become the worst pandemic in modern history. The lack of prior immunity to the virus has resulted in a high mortality rate, though children have fared better than adults, overall. We present a case of a child who developed B-cell acute lymphoblastic leukemia 1 week following a symptomatic COVID-19 infection. It is possible that this viral infection provided the "second hit" posited to occur in pediatric leukemogenesis as proposed by Dr Greaves, with his initial viral exposure occurring several weeks earlier.

Original languageEnglish
Pages (from-to)e1241-e1243
JournalJournal of Pediatric Hematology/Oncology
Volume43
Issue number8
DOIs
StatePublished - Nov 1 2021

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