Comparative Growth Outcomes in Preterm Infants Fed Either Mother's Own Milk or Donor Human Milk

Pradeep Kumar Velumula, Faesal Elbakoush, Hiba Elfadeel, Mirjana Lulic-Botica, Girija Natarajan, Monika Bajaj

Research output: Contribution to journalArticlepeer-review


Objective: To compare growth velocity (GV) in preterm infants fed mother's own milk (MOM) fortified with human milk-based fortifier (HMBF) to those who received donor human milk (DHM) fortified with HMBF. Study Design: A retrospective study of preterm infants with birth weight <1,250 g receiving an exclusive human milk diet. Maternal and infant charts were reviewed for feeding, growth, and short-term neonatal morbidities. Results: On regression analysis, after adjusting (gestational age, multiple births, antenatal steroids, and small for gestational age), no significant difference was observed between the two groups in GV from birth to 32 weeks postmenstrual age (β-coefficient 0.83, 95% confidence interval [CI]: -0.47 to 2.14, p = 0.21), GV from the day of regaining of birth weight to discharge (β-coefficient -0.015, 95% CI: -1.08 to 1.05, p = 0.98). The rate of Grade 3 and 4 intraventricular hemorrhage was significantly higher in the DHM group (19.6% compared to 5.5% in MOM, p = 0.03). Conclusion: At our institution, there was no difference in GV of preterm infants fed HMBF-fortified MOM versus HMBF-fortified DBM.

Original languageEnglish
Pages (from-to)300-306
Number of pages7
JournalBreastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine
Issue number4
StatePublished - Apr 1 2023


  • donor human milk
  • growth velocity
  • mother's own milk
  • preterm infants
  • short-term neonatal outcomes


Dive into the research topics of 'Comparative Growth Outcomes in Preterm Infants Fed Either Mother's Own Milk or Donor Human Milk'. Together they form a unique fingerprint.

Cite this