Comparison of nebulized magnesium sulfate plus albuterol to nebulized albuterol plus saline in children with acute exacerbations of mild to moderate asthma

Prashant Mahajan, Demetris Haritos, Norman Rosenberg, Ronald Thomas

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

A prospective, randomized, double blinded study was conducted to determine whether a combination of nebulized magnesium sulfate and albuterol as a single dose adds any benefit in management of children with mild to moderate asthma when compared to nebulized albuterol with saline. The difference in FEV1 was significant at 10 and 20 min after a single dose of the combined treatment with magnesium and albuterol when compared with the albuterol and saline group (1.41 L ± 0.53 vs. 1.13 L ± 0.34, respectively, p = 0.03). The addition of magnesium to albuterol seems to provide short-term benefits in children with acute exacerbations of mild to moderate asthma.

Original languageEnglish
Pages (from-to)21-25
Number of pages5
JournalJournal of Emergency Medicine
Volume27
Issue number1
DOIs
StatePublished - Jul 2004

Keywords

  • asthma
  • nebulized magnesium sulfate

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