TY - JOUR
T1 - Contraceptive Methods and the Impact of Menstruation on Daily Functioning in Women with Sickle Cell Disease
AU - Day, Melissa E.
AU - Stimpson, Sarah Jo
AU - Rodeghier, Mark
AU - Ghafuri, Djamila
AU - Callaghan, Michael
AU - Zaidi, Ahmar Urooj
AU - Hannan, Bryan
AU - Kassim, Adetola
AU - James, Andra H.
AU - Debaun, Michael R.
AU - Sharma, Deva
N1 - Funding Information:
The authors thank the individuals with SCD who were participants in the study. We also recognize the support of the DeBaun research laboratory members and Wayne State University, Division of Pediatric Hematology Oncology faculty for their collaboration efforts. M.E.D. and D.S. acknowledge the Doris Duke Charitable Foundation and the Foundation for Women and Girls with Blood Disorders for their funding support, respectively.
Publisher Copyright:
© 2019 Lippincott Williams & Wilkins.
PY - 2019/3/1
Y1 - 2019/3/1
N2 - Objectives Women with sickle cell disease (SCD) are living longer as a result of advances in the care of their underlying disease. With the population growing of women living with SCD, reproductive health issues in this population have become an emphasized area of medical care. We sought to describe current patterns of contraception use, menstruation, and quality-of-life (QOL) measures in women with SCD. Methods Using a cross-sectional study design, we administered paper surveys at two academic medical centers to women aged 10 to 55 years with SCD to capture current contraceptive use, characteristics of menstrual cycles, and QOL metrics. Results Of the 103 women who participated, 12.7% (13/102) experienced a duration of menses >7 days (defined here as prolonged menstrual bleeding). Approximately half of women (51.5%, 53/103) used some form of contraception, with depot medroxyprogesterone acetate injections and condoms being the most common. During their last menstrual periods, women with both dysmenorrhea and prolonged menstrual bleeding (6.9%, 7/102) were more likely to experience more days of poor QOL, with more nights with sleep disturbance (P = 0.001) and more days with trouble taking care of themselves (P = 0.003), as well as being unable to do things they previously enjoyed (P = 0.001), compared with those with neither phenomenon (28.2%, 29/103). Conclusions Dysmenorrhea and prolonged menstrual bleeding negatively affect the QOL of women with SCD. Menstrual histories and preventive measures for menstruation-related morbidity should be incorporated into routine evaluations of women with SCD.
AB - Objectives Women with sickle cell disease (SCD) are living longer as a result of advances in the care of their underlying disease. With the population growing of women living with SCD, reproductive health issues in this population have become an emphasized area of medical care. We sought to describe current patterns of contraception use, menstruation, and quality-of-life (QOL) measures in women with SCD. Methods Using a cross-sectional study design, we administered paper surveys at two academic medical centers to women aged 10 to 55 years with SCD to capture current contraceptive use, characteristics of menstrual cycles, and QOL metrics. Results Of the 103 women who participated, 12.7% (13/102) experienced a duration of menses >7 days (defined here as prolonged menstrual bleeding). Approximately half of women (51.5%, 53/103) used some form of contraception, with depot medroxyprogesterone acetate injections and condoms being the most common. During their last menstrual periods, women with both dysmenorrhea and prolonged menstrual bleeding (6.9%, 7/102) were more likely to experience more days of poor QOL, with more nights with sleep disturbance (P = 0.001) and more days with trouble taking care of themselves (P = 0.003), as well as being unable to do things they previously enjoyed (P = 0.001), compared with those with neither phenomenon (28.2%, 29/103). Conclusions Dysmenorrhea and prolonged menstrual bleeding negatively affect the QOL of women with SCD. Menstrual histories and preventive measures for menstruation-related morbidity should be incorporated into routine evaluations of women with SCD.
KW - contraception
KW - dysmenorrhea
KW - prolonged menstrual bleeding
KW - quality of life
KW - sickle cell disease
UR - http://www.scopus.com/inward/record.url?scp=85062325095&partnerID=8YFLogxK
U2 - 10.14423/SMJ.0000000000000949
DO - 10.14423/SMJ.0000000000000949
M3 - Article
C2 - 30830232
AN - SCOPUS:85062325095
VL - 112
SP - 174
EP - 179
JO - Southern Medical Journal
JF - Southern Medical Journal
SN - 0038-4348
IS - 3
ER -