Copper and iron ions accelerate the prion-like propagation of α-synuclein: A vicious cycle in Parkinson's disease

Pharmacology, Toxicology and Pharmaceutical Science

• Synuclein 100%
• Copper 60%
• Iron 60%
• Parkinson Disease 50%
• Diseases 10%
• Protein 10%
• Pathogenesis 10%
• Metal Ion 10%
• Heavy Metal 10%
• Transcellular 10%
• Disease Model 10%
• Deferiprone 10%
• Apoptosis 10%
• Trientine 10%
• Chelating Agent 10%
• Lewy Body 10%
• Proteoheparan Sulfate 10%

Biochemistry, Genetics and Molecular Biology

• Synuclein 100%
• Prion 50%
• Iron Ion 50%
• Copper 40%
• Internalization 20%
• Copper Ion 20%
• Membrane 10%
• Lifespan 10%
• Apoptosis 10%
• Proteoglycan 10%
• Heparan Sulfate 10%
• Health 10%
• Drive 10%
• Caenorhabditis elegans 10%
• Iron 10%
• Protein 10%