Disseminated histoplasmosis leading to end stage liver failure in immunocompetent patient: case report and review of literature.

Darshan Gandhi, Tanmay Gandhi, Adam Wolfe, Asim Kichloo, Jagmeet Singh, Kenneth P. Batts, Love Patel

Research output: Contribution to journalArticlepeer-review

Abstract

Histoplasmosis is the fungal infection caused by Histoplasma capsulatum fungus. It is commonly found in a few endemic areas in the United States, where there is a large number of birds or bats and can spread through their droppings. Disseminated histoplasmosis is a severe manifestation of the fungal infection which is commonly seen in individuals with underlying immunosuppression. Our case is an unusual case of disseminated histoplasmosis in a 60-year-old, immunocompetent male patient with a history of significant alcohol abuse, which led to end stage liver failure. While the patient showed some signs of improvement initially upon beginning the treatment, he ultimately continued to deteriorate despite treatment due to an overwhelming histoplasmosis infection. This case demonstrates the importance of keeping a high index of suspicion even amongst immunocompetent patients with no obvious exposure to risk factors. It also shows that timely diagnosis with a high index of suspicion is required with an integrated treatment approach.

Original languageEnglish
Pages (from-to)2214-2219
Number of pages6
JournalRadiology Case Reports
Volume16
Issue number8
DOIs
StatePublished - Aug 2021

Keywords

  • CT scan
  • Disseminated histoplasmosis
  • Fungal
  • Histoplasmosis
  • Infection
  • USG

Fingerprint

Dive into the research topics of 'Disseminated histoplasmosis leading to end stage liver failure in immunocompetent patient: case report and review of literature.'. Together they form a unique fingerprint.

Cite this