Duffy-Null Phenotype-Associated Neutropenia is the Most Common Etiology for Leukopenia/Neutropenia Referrals to a Tertiary Children's Hospital

Kelsey Gay; Kristopher Dulay; Yaddanapudi Ravindranath; Süreyya Savaşan

doi:10.1016/j.jpeds.2023.113608

Duffy-Null Phenotype-Associated Neutropenia is the Most Common Etiology for Leukopenia/Neutropenia Referrals to a Tertiary Children's Hospital

Kelsey Gay, Kristopher Dulay, Yaddanapudi Ravindranath, Süreyya Savaşan

Research output: Contribution to journal › Article › peer-review

Abstract

Duffy-null phenotype-associated neutropenia was present in 77.7% of leukopenia/neutropenia referrals to our center in Detroit with a high prevalence in Yemeni (96.6%), African American (91%), and non-Yemeni Middle Eastern (52.9%) patients. Greater availability of Duffy typing in patients with neutropenia but without recurrent/frequent/serious infections may lessen the need for additional consultations and investigations.

Original language	English
Article number	113608
Journal	Journal of Pediatrics
Volume	262
DOIs	https://doi.org/10.1016/j.jpeds.2023.113608
State	Published - Nov 2023

Keywords

African
Duffy-null phenotype
Middle Eastern
Yemeni
benign ethnic neutropenia

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10.1016/j.jpeds.2023.113608

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title = "Duffy-Null Phenotype-Associated Neutropenia is the Most Common Etiology for Leukopenia/Neutropenia Referrals to a Tertiary Children's Hospital",

abstract = "Duffy-null phenotype-associated neutropenia was present in 77.7% of leukopenia/neutropenia referrals to our center in Detroit with a high prevalence in Yemeni (96.6%), African American (91%), and non-Yemeni Middle Eastern (52.9%) patients. Greater availability of Duffy typing in patients with neutropenia but without recurrent/frequent/serious infections may lessen the need for additional consultations and investigations.",

keywords = "African, Duffy-null phenotype, Middle Eastern, Yemeni, benign ethnic neutropenia",

author = "Kelsey Gay and Kristopher Dulay and Yaddanapudi Ravindranath and S{\"u}reyya Sava{\c s}an",

note = "Publisher Copyright: {\textcopyright} 2023 Elsevier Inc.",

year = "2023",

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doi = "10.1016/j.jpeds.2023.113608",

language = "English",

volume = "262",

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AU - Gay, Kelsey

AU - Dulay, Kristopher

AU - Ravindranath, Yaddanapudi

AU - Savaşan, Süreyya

PY - 2023/11

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N2 - Duffy-null phenotype-associated neutropenia was present in 77.7% of leukopenia/neutropenia referrals to our center in Detroit with a high prevalence in Yemeni (96.6%), African American (91%), and non-Yemeni Middle Eastern (52.9%) patients. Greater availability of Duffy typing in patients with neutropenia but without recurrent/frequent/serious infections may lessen the need for additional consultations and investigations.

AB - Duffy-null phenotype-associated neutropenia was present in 77.7% of leukopenia/neutropenia referrals to our center in Detroit with a high prevalence in Yemeni (96.6%), African American (91%), and non-Yemeni Middle Eastern (52.9%) patients. Greater availability of Duffy typing in patients with neutropenia but without recurrent/frequent/serious infections may lessen the need for additional consultations and investigations.

KW - African

KW - Duffy-null phenotype

KW - Middle Eastern

KW - Yemeni

KW - benign ethnic neutropenia

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DO - 10.1016/j.jpeds.2023.113608

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AN - SCOPUS:85165906606

SN - 0022-3476

VL - 262

JO - Journal of Pediatrics

JF - Journal of Pediatrics

M1 - 113608

ER -

Duffy-Null Phenotype-Associated Neutropenia is the Most Common Etiology for Leukopenia/Neutropenia Referrals to a Tertiary Children's Hospital

Abstract

Keywords

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