TY - JOUR
T1 - Effect of an exclusive human milk diet on feeding tolerance in preterm infants
AU - El-Fadeel, Hiba
AU - Velumula, Pradeep
AU - Lulic-Botica, Mirjana
AU - Natarajan, Girija
AU - Thomas, Ronald
AU - Botica, Gabriella
AU - Bajaj, Monika
N1 - Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer Nature America, Inc.
PY - 2022/8
Y1 - 2022/8
N2 - Objective: To compare the time to full enteral feeds in preterm infants fed exclusive human milk (EHM) - mother’s own milk (MOM) fortified with human milk-based fortifier (HMBF), to those who received partial human milk (PHM) - MOM fortified with bovine milk-based fortifier (BMBF), and exclusive formula. Study design: A single-center retrospective study of infants with birth weight <1250 g from 2013 to 2018. Data on feeding, growth and other short-term neonatal morbidities were collected. Results: On regression analysis, time to full enteral feeds was significantly higher in PHM compared to EHM group (β-coefficient 4.14, 95% CI 0.00–8.29) and formula-fed group compared to EHM (β-coefficient 4.3, 95% CI 0.32–8.20). No significant differences in growth velocity, length of stay and other morbidities were found between the groups. Conclusion: Infants in EHM had better feeding tolerance and reached their enteral feed goals sooner compared to PHM and formula-fed groups.
AB - Objective: To compare the time to full enteral feeds in preterm infants fed exclusive human milk (EHM) - mother’s own milk (MOM) fortified with human milk-based fortifier (HMBF), to those who received partial human milk (PHM) - MOM fortified with bovine milk-based fortifier (BMBF), and exclusive formula. Study design: A single-center retrospective study of infants with birth weight <1250 g from 2013 to 2018. Data on feeding, growth and other short-term neonatal morbidities were collected. Results: On regression analysis, time to full enteral feeds was significantly higher in PHM compared to EHM group (β-coefficient 4.14, 95% CI 0.00–8.29) and formula-fed group compared to EHM (β-coefficient 4.3, 95% CI 0.32–8.20). No significant differences in growth velocity, length of stay and other morbidities were found between the groups. Conclusion: Infants in EHM had better feeding tolerance and reached their enteral feed goals sooner compared to PHM and formula-fed groups.
UR - http://www.scopus.com/inward/record.url?scp=85124819604&partnerID=8YFLogxK
U2 - 10.1038/s41372-022-01348-y
DO - 10.1038/s41372-022-01348-y
M3 - Article
C2 - 35184144
AN - SCOPUS:85124819604
SN - 0743-8346
VL - 42
SP - 1070
EP - 1075
JO - Journal of Perinatology
JF - Journal of Perinatology
IS - 8
ER -