Effect of manufacturing process on the biocompatibility and mechanical properties of Ti-30Ta alloy

P. Gill, N. Munroe, C. Pulletikurthi, S. Pandya, W. Haider

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Ti alloys have been widely used in the aerospace, chemical, and biomedical industries for their high strength/weight ratio and corrosion resistance. However, Nitinol's usage in the latter industry has been fraught with concerns of allergic and toxic effects of Ni released from implants. Recently, much attention has been placed on the development of Ni-free Ti-Ta alloys, which are considered prime candidates for applications such as metal-on-metal spinal disk replacements, orthopedic implants, cardiovascular stents, dental posts, and guide wires. In this research, the biocompatibility of Ti-30Ta alloys manufactured by powder metallurgy (PM) and arc melting (ARC) were investigated. The corrosion resistance of each alloy was determined in accordance with ASTM F 2129-08 in phosphate buffered saline (PBS) and PBS with amino acids at 37 °C. The concentration of metal ions released during corrosion was measured by Inductively Coupled Plasma Mass Spectroscopy (ICP-MS). Scanning Electron Microscopy (SEM) was used to assess the morphology of the alloys before and after corrosion. Vicker's hardness tests were performed to compare the hardness and tensile strength of the alloys. Human osteoblast cells were successfully grown on the surface of both alloys.

Original languageEnglish
Pages (from-to)819-823
Number of pages5
JournalJournal of Materials Engineering and Performance
Issue number4-5
StatePublished - Jul 2011


  • Biocompatibility
  • Corrosion
  • Osteointegration


Dive into the research topics of 'Effect of manufacturing process on the biocompatibility and mechanical properties of Ti-30Ta alloy'. Together they form a unique fingerprint.

Cite this