Electrochemical behavior and biological response of Mesenchymal Stem Cells on cp-Ti after N-ions implantation

M. Rizwan, A. Ahmad, K. M. Deen, W. Haider

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Titanium and its alloys are most widely used as implant materials due to their excellent biocompatibility, mechanical properties and chemical stability. In this study Nitrogen ions of known dosage were implanted over cp-Ti by Pelletron accelerator with beam energy of 0.25 MeV.The atomic force microscopy of bare and nitrogen implanted specimens confirmed increase in surface roughness with increase in nitrogen ions concentration. X-ray diffraction patterns of ions implanted surfaces validated the formation of TiN 0.3 and Ti 3 N 2-x nitride phases. The tendency to form passive film and electrochemical behavior of these surfaces in ringer lactate (RL) solution was evaluated by Potentiodynamic polarization and electrochemical impedance spectroscopy respectively. It is proved that nitrogen ions implantation was beneficial to reduce corrosion rate and stabilizing passive film by increasing charge transfer resistance in RL. It was concluded that morphology and proliferation of Mesenchymal Stem Cells on nitrogen ions implanted surfaces strongly depends on surface roughness and nitride phases.

Original languageEnglish
Pages (from-to)718-724
Number of pages7
JournalApplied Surface Science
StatePublished - Nov 30 2014


  • Corrosion
  • Electrochemical
  • Ions implantation
  • STEM cells


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