Enhanced resting left ventricular filling in patients with successful coarctation repair and exercise-induced hypertension

M. V.T. Tantengco, R. D. Ross, R. A. Humes, N. M. Sullivan, V. M. Joshi, S. K. Clapp, M. L. Epstein

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

M-mode and Doppler echocardiographic analyses of left ventricular (LV) shortening and filling were performed in 50 patients who underwent coarctectomy (median follow-up 9.5 years) and in 16 athletes in a control group before an exercise stress test with upright bicycle ergometry was performed. Thirty-two of 50 patients and 18 of 50 patients had a normotensive and hypertensive response to exercise, respectively. Preexercise echocardiographic data were compared among the control, normotensive, and hypertensive patient groups. LV peak filling rates (dD/dt, diastole) were increased in the hypertensive group (18.3 ± 3.5) compared with those in the normotensive group (14.4 ± 3.2; p < 0.001) and the control group (13.6 ± 2.8; p < 0.001). LV shortening was enhanced in the coarctectomy group with that in the control group. Therefore patients with successful coarctectomy in childhood have enhanced LV shortening and relaxation at rest. Demonstration of enhanced LV peak filling rates may help identify patients at risk for exercise-induced hypertension.

Original languageEnglish
Pages (from-to)1082-1088
Number of pages7
JournalAmerican Heart Journal
Volume134
Issue number6
DOIs
StatePublished - 1997

Fingerprint

Dive into the research topics of 'Enhanced resting left ventricular filling in patients with successful coarctation repair and exercise-induced hypertension'. Together they form a unique fingerprint.

Cite this