Abstract
In the course of our screening for small molecule modulators of erythropoietin gene expression, two novel sesquiterpene tropolones and pycnidone were isolated from a culture of OS-F69284 (ATCC 74390). Their structures were elucidated by extensive 1H and 13C NMR spectroscopic studies and chemical reactions. These compounds induced erythropoietin gene expression 5-fold at a concentration of 1-1.6 μM.
Original language | English |
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Pages (from-to) | 791-795 |
Number of pages | 5 |
Journal | Journal of Natural Products |
Volume | 61 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1998 |
Externally published | Yes |