Evaluation of Musculoskeletal Disorders with PET, PET/CT, and PET/MR Imaging

Karen Chen, Judy Blebea, Jean Denis Laredo, Wengen Chen, Abass Alavi, Drew A. Torigian

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


18F-2-fluoro-2-deoxy-D-glucose-PET has an established role in the evaluation of hip periprosthetic infection and musculoskeletal malignancies. Determination of its role in the management of inflammatory arthritis and diabetic foot complications is ongoing. The reintroduction of fluorine F 18 sodium fluoride as a PET radiotracer may advantageously replace technetium Tc 99 m methylene diphosphonate for some non-oncologic applications, including treatment monitoring of Paget's disease andfibrous dysplasia. The combination of CT or MR imaging with PET imaging synergistically maximizes the diagnostic potential of a combined structural-functional imaging approach for the detection, characterization, and monitoring of myriad musculoskeletal disorders.

Original languageEnglish
Pages (from-to)451-465
Number of pages15
JournalPET Clinics
Issue number3
StatePublished - Jul 2008


  • Arthroplasty
  • Diabetic foot
  • Metabolic bone disease
  • Musculoskeletal
  • Oncology
  • PET/CT
  • Positron emission tomography (PET)


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