Executive function in CHARGE syndrome

Research output: Contribution to journalArticlepeer-review

Abstract

This study addressed the presence of executive dysfunction in children with CHARGE syndrome, a genetic disorder with multiple physical anomalies and severe challenging behaviors. Ninety-eight children were included in the study. More than half received clinically significant scores on the Behavior Rating Inventory of Executive Function (BRIEF; Gioia et al., 2000) scales of Shift, Monitor, and the Behavioral Regulation Index, with additional high scores on Inhibit and the Global Executive Composite. Associations were found with the age the child first walked, scores on the Autism Behavior Checklist (ABC; Krug et al., 1993), and being classified as deafblind. Difficulties with making transitions and flexible problem solving, monitoring their work and their effect on others, and acting on impulse, may be related to the behavioral difficulties exhibited by children with CHARGE. Interventions targeting improved self-regulation may help to manage this challenging behavior.

Original languageEnglish
Pages (from-to)333-344
JournalChild Neuropsychology
Volume13
StatePublished - 2007

Fingerprint

Dive into the research topics of 'Executive function in CHARGE syndrome'. Together they form a unique fingerprint.

Cite this