The growth of online education has become a global phenomenon driven by emergence of new technologies, widespread adoption of the Internet, and intensifying demand for a skilled workforce for a digital economy. Online education is no longer a trend; it is slowly but surely becoming mainstream by 2025. This paper explores all efforts, accomplishments, issues, challenges, conclusions, and recommendations on this theme through meta-analysis of over 100 published papers since 2000. Through thorough content analysis, we provide useful recommendations for researchers and practitioners working in academia, industry, or government. We also propose a holistic model of interactions between diverse entities and stakeholders in the online tertiary business discipline education industry. This model will certainly be applicable with minor changes to other disciplines and other levels of education—primary and secondary. This model can be tested in piecemeal fashion by researchers using appropriate research methodology.