First-line treatment in open-angle glaucoma: An update

Suzanne A. Turner, Andrew I. McNaught

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


This review paper sets out to evaluate the evidence for different modalities as first-line treatments for primary open-angle glaucoma. In current practice, initial treatment is commonly with medical therapy, whereas laser, or incisional surgery, is performed if medical therapy does not satisfactorily reduce initial intra-ocular pressure and/or prevent visual field progression. However, medical therapy is not without adverse effects, and poor compliance with treatment means that in some cases another primary therapy might be preferable. Glaucoma is a common, chronic disease requiring life-long care in order to prevent progressive optic nerve head atrophy and blindness. Demographic changes in the developed world are resulting in a growing treated population: issues concerning acceptability, efficiency and cost-effectiveness of initial glaucoma treatment will become increasingly important.

Original languageEnglish
Pages (from-to)587-594
Number of pages8
JournalExpert Review of Ophthalmology
Issue number6
StatePublished - 2013


  • ALT
  • Alpha-agonist
  • Beta-blocker
  • Carbonic anhydrase inhibitor
  • Medical treatment
  • Open-angle glaucoma
  • Prostaglandin
  • SLT
  • Trabeculectomy
  • Trabeculoplasty


Dive into the research topics of 'First-line treatment in open-angle glaucoma: An update'. Together they form a unique fingerprint.

Cite this