Five-loop coil occlusion of patent ductus arteriosus prevents recurrence of shunt at follow-up

P. Syamasundar Rao, Ian C. Balfour, Saadeh B. Jureidini, Gautam K. Singh, Su Chiung Chen

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Recent reports suggest reopening of the patent ductus arteriosus (PDA) after complete occlusion with three-loop Gianturco coils. We hypothesize that five-loop coils may produce a larger thrombus than three-loop coils, which will result in no or less probability of recanalization of PDA during follow- up. This study is designed to test this hypothesis. Follow-up echocardiographic and Doppler data of 30 patients who underwent five-loop coil occlusion of small to medium-sized PDA during a 33-month period ending December 1998 were examined. Thirty patients had no residual shunt on echo Doppler study on the day following the procedure and were followed for 6 to 30 months (median, 12) after coil implantation. At the last follow-up study, none of the patients had a residual shunt and left atrial size decreased. Careful pulsed, continuous wave, and color Doppler interrogation of left/main pulmonary artery junction and proximal descending aorta did not reveal any evidence for obstruction. The follow-up data suggest that complete occlusion of small-to medium-sized PDAs is feasible with five-loop coils without evidence for recanalization at a mean follow-up of 12 months. Much longer (2 to 5 years) follow-up data may be necessary to confirm these observations. We speculate that a greater degree of thrombosis is produced within the ductus by the five-loop coils, which in turn may be responsible for lack of shunt recurrence. We recommend use of five-loop instead of three-loop coils for transcatheter occlusion of small- to medium-sized PDAs. (C) 2000 Wiley-Liss, Inc.

Original languageEnglish
Pages (from-to)202-206
Number of pages5
JournalCatheterization and Cardiovascular Interventions
Issue number2
StatePublished - 2000


  • Gianturco coils
  • Patent ductus arteriosus
  • Transcatheter occlusion


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