Hibernation and stunning of the myocardium

Robert A. Kloner, Karin Przyklenk

Research output: Contribution to journalEditorial

60 Scopus citations


Less than 20 years ago, contractile dysfunction of the myocardium in patients with coronary-artery narrowing was thought to be caused by either irreversible damage to myocytes (that is, myocardial infarction or scarring) or reversible ischemia (such as would occur during an attack of angina). During the past decade, however, both clinical and laboratory studies have demonstrated that contractile dysfunction in the heart may also occur in the absence of a myocardial infarction or after an acute ischemic event is over.1 Specifically, two phenomena may account for this contractile dysfunction of viable myocytes: hibernating myocardium or stunned myocardium. The report by. .

Original languageEnglish
Pages (from-to)1877-1879
Number of pages3
JournalNew England Journal of Medicine
Issue number26
StatePublished - Dec 26 1991


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