Hypercalcemia in pediatric acute megakaryocytic leukemia: Case report and review of the literature

Muna Qayed, Ibrahim Ahmed, Rudolph P. Valentini, Barbara Cushing, Madhvi Rajpurkar

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Hypercalcemia has been described as a possible complication of many pediatric malignancies. Here, we report an 8-month-old non-Down syndrome infant with acute megakaryocytic leukemia and severe hypercalcemia at presentation. A review of the literature reveals that this is the first case of hypercalcemia complicating acute megakaryocytic leukemia reported in the pediatric literature. His initial workup, and the course of management and outcome, is described in detail. Though the etiology of this complication remains unclear, our experience suggests that early institution of chemotherapy along with supportive care is the best treatment for control of hypercalcemia.

Original languageEnglish
Pages (from-to)373-376
Number of pages4
JournalJournal of Pediatric Hematology/Oncology
Volume31
Issue number5
DOIs
StatePublished - May 2009

Keywords

  • Acute megakaryocytic leukemia
  • Hypercalcemia
  • Pamidronate
  • Pediatric

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