In vitro and in vivo efficacy of a herbal formulation against skin infections

Padma Deshmukh, Pooja Gupta, Ravi Shankar

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Skin infections and resistance development are major problems in India. An herbal gel consisting of six medicinal plants viz: Curcuma longa, Berberis aristata, Citrus reticulate, Ficus reliogosa, Mangifera indica and Mesua ferrea was screened for its antibacterial activity against resistant strains of Staphylococcus aureus, Pseudomonas aeruginosa and Corynebacterium spp., the most implicated organisms in case of skin infections. Skin toxicity tests performed revealed that the herbal gel did not posses any. toxic effects. Bactericidal efficacy of the herbal gel was found to be 100% within 2 hours of contact as compared to 3 hours in case of Benzoyl peroxide. Complete clearance of infection with no scaly or dry skin remnants was observed after 20 days in case of animal simulation models.

Original languageEnglish
Pages (from-to)199-204
Number of pages6
JournalJournal of Pure and Applied Microbiology
Issue number1
StatePublished - Apr 2009


  • Benzoyl peroxide
  • Herbal gel
  • Skin infections
  • Skin toxicity


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