Increased atrial natriuretic factor response to exercise after coarctation repair

Robert D. Ross, Sandra K. Clapp, Stephen Gunther, Stephen M. Paridon, Richard A. Humes, Zia Q. Farooki, William W. Pinsky

Research output: Contribution to journalArticlepeer-review

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Atrial natriuretic factor (ANF) is primarily secreted in response to stretching of the atrial tissue.1 Recent evidence suggests that owing to its natriuretic and vasorelaxant properties, ANF may be involved in the regulation of blood pressure.2 Because children who have undergone repair of coarctation of the aorta have a propensity for either resting or exercise-related hypertension later in life, this study was designed to evaluate the response of ANF to dynamic exercise many years after coarctation repair and compare the results with those of an age-matched control group.

Original languageEnglish
Pages (from-to)1370-1372
Number of pages3
JournalThe American Journal of Cardiology
Issue number16
StatePublished - May 15 1992


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