Ischemic Conditioning Attenuates Platelet-Mediated Thrombosis

Karin Przyklenk, Peter Whittaker

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Data obtained in both preclinical models and humans have revealed that the favorable cardiac consequences of ischemic conditioning extend beyond a direct effect on the cardiomyocyte. In the current review, we summarize our as-yet limited understanding of the complex relationships between ischemic conditioning, platelet activation-aggregation, and cardioprotection.

Original languageEnglish
Pages (from-to)391-396
Number of pages6
JournalJournal of Cardiovascular Pharmacology and Therapeutics
Volume22
Issue number5
DOIs
StatePublished - Sep 1 2017

Keywords

  • P-selectin
  • ischemic preconditioning
  • monocyte-platelet aggregates
  • neutrophil-platelet aggregates
  • platelet
  • remote ischemic conditioning
  • thrombosis

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