TY - JOUR
T1 - Ischemic Conditioning Attenuates Platelet-Mediated Thrombosis
AU - Przyklenk, Karin
AU - Whittaker, Peter
N1 - Publisher Copyright:
© 2017 Author(s).
PY - 2017/9/1
Y1 - 2017/9/1
N2 - Data obtained in both preclinical models and humans have revealed that the favorable cardiac consequences of ischemic conditioning extend beyond a direct effect on the cardiomyocyte. In the current review, we summarize our as-yet limited understanding of the complex relationships between ischemic conditioning, platelet activation-aggregation, and cardioprotection.
AB - Data obtained in both preclinical models and humans have revealed that the favorable cardiac consequences of ischemic conditioning extend beyond a direct effect on the cardiomyocyte. In the current review, we summarize our as-yet limited understanding of the complex relationships between ischemic conditioning, platelet activation-aggregation, and cardioprotection.
KW - P-selectin
KW - ischemic preconditioning
KW - monocyte-platelet aggregates
KW - neutrophil-platelet aggregates
KW - platelet
KW - remote ischemic conditioning
KW - thrombosis
UR - http://www.scopus.com/inward/record.url?scp=85020484453&partnerID=8YFLogxK
U2 - 10.1177/1074248417724871
DO - 10.1177/1074248417724871
M3 - Article
C2 - 28793820
AN - SCOPUS:85020484453
SN - 1074-2484
VL - 22
SP - 391
EP - 396
JO - Journal of Cardiovascular Pharmacology and Therapeutics
JF - Journal of Cardiovascular Pharmacology and Therapeutics
IS - 5
ER -