Isolation and characterization of the mouse (Mus musculus) somatostatin receptor type-4-encoding gene (mSSTR4)

Wolfgang Schwabe, Miles B. Brennan, Ute Hochgeschwender

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

We have isolated and sequenced the mouse somatostatin receptor subtype-4-encoding gene (mSSTR4). The mSSTR4 gene encodes 384 amino acids (aa). The deduced mouse SSTR4 has 95 and 89% aa identity with the deduced rat and human SSTR4, respectively, while it has lower aa identity with the other mouse subtypes (mSSTR1, 60%; mSSTR2 47%, mSSTR3, 42%). Using an RT-PCR technique, we show that the mSSTR4 gene is expressed in brain, but not in liver, heart, spleen or kidney of the adult mouse.

Original languageEnglish
Pages (from-to)233-235
Number of pages3
JournalGene
Volume168
Issue number2
DOIs
StatePublished - Feb 12 1996

Keywords

  • Expression
  • Gene cloning
  • Nucleotide sequence
  • Oligodeoxynucleotide hybridization
  • RT-PCR

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