TY - JOUR
T1 - Isolation and characterization of the mouse (Mus musculus) somatostatin receptor type-4-encoding gene (mSSTR4)
AU - Schwabe, Wolfgang
AU - Brennan, Miles B.
AU - Hochgeschwender, Ute
PY - 1996/2/12
Y1 - 1996/2/12
N2 - We have isolated and sequenced the mouse somatostatin receptor subtype-4-encoding gene (mSSTR4). The mSSTR4 gene encodes 384 amino acids (aa). The deduced mouse SSTR4 has 95 and 89% aa identity with the deduced rat and human SSTR4, respectively, while it has lower aa identity with the other mouse subtypes (mSSTR1, 60%; mSSTR2 47%, mSSTR3, 42%). Using an RT-PCR technique, we show that the mSSTR4 gene is expressed in brain, but not in liver, heart, spleen or kidney of the adult mouse.
AB - We have isolated and sequenced the mouse somatostatin receptor subtype-4-encoding gene (mSSTR4). The mSSTR4 gene encodes 384 amino acids (aa). The deduced mouse SSTR4 has 95 and 89% aa identity with the deduced rat and human SSTR4, respectively, while it has lower aa identity with the other mouse subtypes (mSSTR1, 60%; mSSTR2 47%, mSSTR3, 42%). Using an RT-PCR technique, we show that the mSSTR4 gene is expressed in brain, but not in liver, heart, spleen or kidney of the adult mouse.
KW - Expression
KW - Gene cloning
KW - Nucleotide sequence
KW - Oligodeoxynucleotide hybridization
KW - RT-PCR
UR - http://www.scopus.com/inward/record.url?scp=0030056353&partnerID=8YFLogxK
U2 - 10.1016/0378-1119(95)00748-2
DO - 10.1016/0378-1119(95)00748-2
M3 - Article
C2 - 8654950
AN - SCOPUS:0030056353
SN - 0378-1119
VL - 168
SP - 233
EP - 235
JO - Gene
JF - Gene
IS - 2
ER -