Light path-length distributions within the retina

Paul I. Rodmell, John A. Crowe, Alastair Gorman, Andrew R. Harvey, Gonzalo Muyo, David J. Mordant, Andy I. McNaught, Stephen P. Morgan

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


A Monte Carlo simulation of light propagation through the retina has been developed to understand the path-length distributions within the retinal vessel. For full-field illumination, the path-length distribution within the vessel comprises directly backscattered light and light that has passed once or twice through the vessel. The origins of these light path-length distributions can be better understood by investigating different combinations of single-point illumination and detection positions. Perhaps the most significant observation is that illumination at the edges of the vessel, rather than over the whole field of view, and detection directly above the vessel capture only the light that has taken a single pass through the vessel. This path-length distribution is tightly constrained around the diameter of the vessel and can potentially provide enhancements for oxygen saturation imaging. The method could be practically implemented using an offset-pinhole confocal imaging system or structured light illumination.

Original languageEnglish
Article number036008
JournalJournal of Biomedical Optics
Issue number3
StatePublished - Mar 2014


  • Monte-Carlo
  • confocal
  • retinal oximetry
  • structured illumination


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