@article{8c20a9446be94d458abc3a962d8f405a,
title = "Magnetic resonance imaging in juvenile rheumatoid arthritis",
abstract = "Objectives: This study was undertaken to examine the role of magnetic resonance imaging (MRI) in the management of patients with juvenile rheumatoid arthritis (JRA). Methods: A Medline search was performed to identify all publications pertaining to MRI in JRA. Further searches and identification of articles from bibliographies identified articles pertaining to plain radiograph imaging in JRA and MRI in adult rheumatoid arthritis. Results: Studies in both children and adults have shown superiority of MRI to plain radiography in detecting synovial hypertrophy and articular cartilage abnormalities. Several studies in adults have shown a good correlation of MR images with gross anatomic as well as histological findings at arthroscopy. Biochemical changes that occur before structural changes within the joint may even be detectable with magnetic resonance spectroscopy. Conclusions: MRI holds promise for the assessment of disease progression in JRA and may be useful in serial evaluation, as in clinical trials.",
keywords = "Assessment, Imaging, Juvenile rheumatoid arthritis, Magnetic resonance imaging",
author = "Graham, {T. B.} and Blebea, {J. S.} and V. Gylys-Morin and Passo, {M. H.}",
note = "Funding Information: From the Special Treatment Center for Juvenile Arthritis and the Department of Radiology, Children's Hospital Medical Center,{"} the University of Cincinnati College of Medicine; and the Department of Radiology, University Hospital, Cincinnati, OH. T. Brent Graham, MD: Clinical Fellow, the Special Treatment Center for Juvenile Arthritis, Children's Hospital Medical Center, and the University of Cincinnati College of Medicine; Judy S. Blebea, MD: Associate Professor, Depa~ment of Radiology, University Hospital, and the University of Cincinnati College of Medicine; Victoria Gylys-Morin, MD: Assistant Professor, Department of Radiology; Children's Hospital Medical Center; and the University of Cincinnati College of Medicine; Murray H. Passo, MD: Professor, the Special Treatment Center for Juvenile Arthritis, Children's Hospital Medical Center, and the University of Cincinnati College of Medicine. Supported in part by the Children's Hospital Research Foundation of Cincinnati, the Schmidlapp Foundation, and the National Institutes of Health (AR42632 and AR44059). Address reprint requests to T. Brent Graham, MD, William S. Rowe Department of Rheumatology, 3333 Burner Ave, Cincinnati, OH 45229. Copyright {\textcopyright} 1997 by W.B. Saunders Company 0049-0172/97/2703-000355. 00/0",
year = "1997",
doi = "10.1016/S0049-0172(97)80015-7",
language = "English",
volume = "27",
pages = "161--168",
journal = "Seminars in Arthritis and Rheumatism",
issn = "0049-0172",
number = "3",
}