Mechanical loading of rigid intramuscular implants

Gerald E. Loeb, Raymond A. Peck, Jasspreet Singh, Young Ho Kim, Sudeep Deshpande, Lucinda L. Baker, J. Timothy Bryant

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Several groups are developing different versions of a new class of leadless, permanently implanted electronic devices with a size and form factor that allows them to be injected into muscles (BIONs™). Their circuitry is protected from body fluids by thin-walled hermetic capsules made from rigid and brittle materials (glass or ceramic) that include feedthroughs to their electrodes. These packages experience repetitive stresses from the very contractions that they excite. We here provide a worst-case analysis of such stresses and methods for testing and validation of devices intended for such usage, along with the failure analysis and remediation strategy for a design that experienced unanticipated failures in vivo.

Original languageEnglish
Pages (from-to)901-910
Number of pages10
JournalBiomedical Microdevices
Issue number6
StatePublished - Dec 2007
Externally publishedYes


  • BION
  • Hermetic encapsulation
  • Intramuscular implants
  • Mechanical loading
  • Neuromuscular stimulation


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