Monoclonal Gammopathy of Renal Significance—A Rare Renal Presentation: A Review of Cases Reported

Asim Kichloo; Najma Nawaz; Jagmeet Singh; Michael Aljadah; Michael Stanley Albosta; Ravinder Bhanot

doi:10.1177/2324709620940500

Monoclonal Gammopathy of Renal Significance—A Rare Renal Presentation: A Review of Cases Reported

Asim Kichloo, Najma Nawaz, Jagmeet Singh, Michael Aljadah, Michael Stanley Albosta, Ravinder Bhanot

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Abstract

Monoclonal gammopathy of undetermined significance is a precursor to multiple myeloma characterized by monoclonal gammopathy without evidence of end organ damage. Some patients with clonal plasma cell disorder that do not meet the requirements for multiple myeloma have been seen to develop pathologic renal disease due to direct effects from deposition of monoclonal protein, referred to as monoclonal gammopathy of renal significance. In this article, we present a rare renal manifestation of monoclonal gammopathy of renal significance as focal segmental glomerulosclerosis.

Original language	English
Journal	Journal of Investigative Medicine High Impact Case Reports
Volume	8
DOIs	https://doi.org/10.1177/2324709620940500
State	Published - 2020

Keywords

focal
gammopathy
glomerulosclerosis
monoclonal

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10.1177/2324709620940500

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abstract = "Monoclonal gammopathy of undetermined significance is a precursor to multiple myeloma characterized by monoclonal gammopathy without evidence of end organ damage. Some patients with clonal plasma cell disorder that do not meet the requirements for multiple myeloma have been seen to develop pathologic renal disease due to direct effects from deposition of monoclonal protein, referred to as monoclonal gammopathy of renal significance. In this article, we present a rare renal manifestation of monoclonal gammopathy of renal significance as focal segmental glomerulosclerosis.",

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AU - Singh, Jagmeet

AU - Aljadah, Michael

AU - Albosta, Michael Stanley

AU - Bhanot, Ravinder

PY - 2020

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N2 - Monoclonal gammopathy of undetermined significance is a precursor to multiple myeloma characterized by monoclonal gammopathy without evidence of end organ damage. Some patients with clonal plasma cell disorder that do not meet the requirements for multiple myeloma have been seen to develop pathologic renal disease due to direct effects from deposition of monoclonal protein, referred to as monoclonal gammopathy of renal significance. In this article, we present a rare renal manifestation of monoclonal gammopathy of renal significance as focal segmental glomerulosclerosis.

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KW - glomerulosclerosis

KW - monoclonal

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ER -

Monoclonal Gammopathy of Renal Significance—A Rare Renal Presentation: A Review of Cases Reported

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