Mood disorder as the presenting manifestation of demyelination

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Objective: To report an unusual presenting manifestation of multiple sclerosis in a teenager. Case Report: We report the case of a 16-year-old male who was diagnosed with schizoaffective disorder a year prior to his neurological consultation. Neurological examination showed evidence of mild lower extremity spasticity with ataxia and dysarthria. Imaging revealed lesions suggestive of multiple sclerosis. Conclusion: An organic basis for psychiatric disorders is often overlooked. Children presenting with symptoms suggestive of a mood disorder, decline in cognition or psychosis deserve a detailed neurological examination and appropriate imaging if indicated, before starting them on antidepressant or neuroleptic medication.

Original languageEnglish
Pages (from-to)104-109
Number of pages6
JournalCase Reports in Neurology
Issue number2
StatePublished - 2013


  • Adolescence
  • Mood disorder
  • Multiple sclerosis


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