Near-triploid acute lymphoblastic leukemia mith TEL/AML1 translocation

Sameer Bakhshi, Meera Chitlur, Barbara Cushing

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

An 11-year-old girl was diagnosed as B-precursor acute lymphoblastic leukemia (ALL) with co-expression of myeloid antigens. Cytogenetic analysis revealed a near-triploid (75-82 chromosomes/cell) abnormal chromosomal complement. Fluroscent in situ hybridization studies indicated presence of TEL/AML1 fusion genes. We discuss the prognostic relevance of TEL/AML1 in this rare neartriploid subtype of ALL.

Original languageEnglish
Pages (from-to)493-495
Number of pages3
JournalIndian Pediatrics
Volume41
Issue number5
StatePublished - May 2004

Keywords

  • Leukemia
  • Triploidy

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