Neurologic disorders of mineral metabolism and parathyroid disease

Lily Agrawal, Zeina Habib, Nicholas V. Emanuele

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

8 Scopus citations


Disorders of mineral metabolism may cause neurologic manifestations of the central and peripheral nervous systems. This is because plasma calcium stabilizes excitable membranes in the nerve and muscle tissue, magnesium is predominantly intracellular and is required for activation of many intracellular enzymes, and extracellular magnesium affects synaptic transmission. This chapter reviews abnormalities in electrolytes and minerals which can be associated with several neuromuscular symptoms including neuromuscular irritability, mental status changes, cardiac and smooth muscle changes, etc.

Original languageEnglish
Title of host publicationHandbook of Clinical Neurology
PublisherElsevier B.V.
Number of pages12
StatePublished - 2014

Publication series

NameHandbook of Clinical Neurology
ISSN (Print)0072-9752


  • Hypercalcemia
  • Hypocalcemia
  • Muscular
  • Neurologic
  • Parathyroid
  • Vitamin D


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