New lupane-type triterpenoid saponins from leaves of Oplopanax horridus (Devil's Club)

Pei Pei Liu, Mo Li, Ting Guo Kang, De Qiang Dou, David C. Smith

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8 Scopus citations


Two new lupane type saponins, along with one known saponin were isolated from leaves of Oplopanax horridus (Devil's Club). The structures of the two new compounds were elucidated as 3α-hydroxy-lup-20(29)-ene-23, 28-dioic acid-3-O-β-D-glucopyranoside (2) and 24-nor-3-oxo-lup-20(29)-en-28-oic acid-28-O-α-L-rhamnopyranosyl(1‴→4″)-β-D- glucopyranosyl( 1′→6′)-β-D-glucopyranoside (3) on the basis of spectroscopic analysis and chemical evidence. The known compound was identified as 3α-hydroxy-lup-20(29)-ene-23, 28-dioic acid (1) by comparison of its spectral data with those reported. Compound 1 was isolated for the first time from the title plant.

Original languageEnglish
Pages (from-to)1019-1022
Number of pages4
JournalNatural Product Communications
Issue number7
StatePublished - 2010
Externally publishedYes


  • Devil's Club
  • Oplopanax horridus
  • Triterpenoid saponin


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