Nosocomial infections and multidrug-resistant bacterial organisms in the pediatric intensive care unit

Eric J. McGrath, Basim I. Asmar

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

Nosocomial infections in Pediatric Intensive Care Units (PICUs) caused by multidrug-resistant bacterial organisms are increasing. This review attempts to report on significant findings in the current literature related to nosocomial infections in PICU settings with an international perspective. The types of nosocomial infections are addressed, including catheter-related bloodstream infections, ventilator-associated pneumonia, urinary tract infections, gastrointestinal infections and postsurgical wound infections. A review of emerging resistant bacterial pathogens includes methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus sp., Clostridium difficile, extended-spectrum β- lactamase producing Gram-negative organisms, Klebsiella pneumoniae carbapenemase-producing strains and multidrug resistant Acinetobacter baumannii. Basic and enhanced infection control methods for the management and control of multidrug-resistant organisms are also summarized with an emphasis on prevention.

Original languageEnglish
Pages (from-to)176-184
Number of pages9
JournalIndian Journal of Pediatrics
Volume78
Issue number2
DOIs
StatePublished - Feb 2011

Keywords

  • Bacterial
  • Multidrug resistant
  • Nosocomial infection
  • PICU
  • Prevention

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