Oral β-Lactam Antibiotics for Pediatric Otitis Media, Rhinosinusitis, and Pneumonia

Leah Molloy, Sasha Barron, Nadia Khan, Evan Abrass, Jocelyn Ang, Nahed Abdel-Haq

Research output: Contribution to journalArticlepeer-review

Abstract

Acute otitis media, acute bacterial rhinosinusitis, and community-acquired pneumonia are major drivers of pediatric antibiotic consumption. With many available options and the added challenges of navigating antibiotic allergies and de-escalating from intravenous treatment for children requiring hospitalization, prescribing for these relatively simple infections can be a source of confusion and error. The purpose of this article is to evaluate the pharmacokinetic and pharmacodynamic properties of antibiotics commonly prescribed for these disease states, and to specifically compare antipneumococcal activity between oral beta-lactams.

Original languageEnglish
Pages (from-to)291-300
Number of pages10
JournalJournal of Pediatric Health Care
Volume34
Issue number3
DOIs
StatePublished - May 1 2020

Keywords

  • Amoxicillin
  • beta-lactams
  • pharmacokinetics

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