Parathyroid Hormone-Related Peptide: A Novel Endocrine Cardioprotective "conditioning Mimetic"

Tanuka Datta, Karin Przyklenk, Nabanita S. Datta

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


An as-yet limited body of evidence suggests that calcium-regulating endocrine hormones - in particular, parathyroid hormone-related peptide (PTHrP) - may have unappreciated cardioprotective effects. The current review focuses on the concept that PTHrP may, via modulation of classic cardioprotective signaling pathways, provide a novel strategy to attenuate myocardial ischemia-reperfusion injury.

Original languageEnglish
Pages (from-to)529-537
Number of pages9
JournalJournal of Cardiovascular Pharmacology and Therapeutics
Issue number6
StatePublished - Nov 1 2017


  • heart
  • ischemia
  • mitogen-activated protein kinase phosphatase 1
  • parathyroid hormone-related peptide
  • reperfusion


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