TY - JOUR
T1 - Pharmacologic Treatment of Pediatric Hypertension
AU - Dhull, Rachita S.
AU - Baracco, Rossana
AU - Jain, Amrish
AU - Mattoo, Tej K.
N1 - Publisher Copyright:
© 2016, Springer Science+Business Media New York.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Prevalence of hypertension is increasing in children and adolescents. Uncontrolled hypertension in children not only causes end organ damage but also increases the risk of adult hypertension and cardiovascular disease. Clinical trials have proven efficacy of antihypertensive medications in children. These medications are well tolerated by children with acceptable safety profile. The choice of agent is usually driven by underlying etiology of hypertension, profile of its side effects, and clinician’s preference. This article will review currently available pediatric data on mechanism of action, common adverse effects, pediatric indication, recent clinical trial, and newer drugs in the common classes of antihypertensive medications.
AB - Prevalence of hypertension is increasing in children and adolescents. Uncontrolled hypertension in children not only causes end organ damage but also increases the risk of adult hypertension and cardiovascular disease. Clinical trials have proven efficacy of antihypertensive medications in children. These medications are well tolerated by children with acceptable safety profile. The choice of agent is usually driven by underlying etiology of hypertension, profile of its side effects, and clinician’s preference. This article will review currently available pediatric data on mechanism of action, common adverse effects, pediatric indication, recent clinical trial, and newer drugs in the common classes of antihypertensive medications.
KW - Clinical trials
KW - Dosing for hypertension
KW - Hypertension
KW - Hypertension in children
KW - Pharmacologic management
UR - http://www.scopus.com/inward/record.url?scp=84962749972&partnerID=8YFLogxK
U2 - 10.1007/s11906-016-0639-4
DO - 10.1007/s11906-016-0639-4
M3 - Review article
C2 - 27048353
AN - SCOPUS:84962749972
VL - 18
JO - Current Hypertension Reports
JF - Current Hypertension Reports
SN - 1522-6417
IS - 4
M1 - 32
ER -