Pharmacologic Treatment of Pediatric Hypertension

Rachita S. Dhull, Rossana Baracco, Amrish Jain, Tej K. Mattoo

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Prevalence of hypertension is increasing in children and adolescents. Uncontrolled hypertension in children not only causes end organ damage but also increases the risk of adult hypertension and cardiovascular disease. Clinical trials have proven efficacy of antihypertensive medications in children. These medications are well tolerated by children with acceptable safety profile. The choice of agent is usually driven by underlying etiology of hypertension, profile of its side effects, and clinician’s preference. This article will review currently available pediatric data on mechanism of action, common adverse effects, pediatric indication, recent clinical trial, and newer drugs in the common classes of antihypertensive medications.

Original languageEnglish
Article number32
JournalCurrent Hypertension Reports
Volume18
Issue number4
DOIs
StatePublished - Apr 1 2016

Keywords

  • Clinical trials
  • Dosing for hypertension
  • Hypertension
  • Hypertension in children
  • Pharmacologic management

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