Pneumocystis pneumonia with hypogammaglobulinemia in a pediatric patient who underwent heart transplantation

Daiji Takajo, Swati Sehgal, Jennifer Blake, Sanjeev Aggarwal

Research output: Contribution to journalArticlepeer-review

Abstract

A 23-month-old Caucasian female who had heart transplantation (HT) at 11 days of age was diagnosed with Pneumocystis pneumonia (PCP) in the setting of secondary hypogammaglobulinemia (HGG). She was diagnosed with HGG at 5 months of age and had been receiving monthly intravenous immunoglobulin infusion. This is the first case report describing the clinical course of PCP in a pediatric patient with HGG. She developed PCP 23 months after HT even when she was off steroids and was receiving timely IVIG. The case posed some clinical questions regarding PCP prophylaxis and HGG management.

Original languageEnglish
Article numbere13571
JournalTransplant Infectious Disease
Volume23
Issue number4
DOIs
StatePublished - Aug 2021

Keywords

  • heart transplantation
  • hypogammaglobulinemia
  • immunoglobulin
  • pneumocystis pneumonia
  • prophylaxis

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