TY - JOUR
T1 - Posttraumatic stress and depression
T2 - potential pathways to disease burden among heart failure patients
AU - Taylor-Clift, April
AU - Hobfoll, Stevan E.
AU - Gerhart, James I.
AU - Richardson, De Juran
AU - Calvin, James E.
AU - Powell, Lynda H.
N1 - Funding Information:
This research is supported by the Charles J. and Margaret Roberts Fund and a grant [NIH-NHLBI 1P50HL105189] from the Rush Center for Urban Health Equity.
Publisher Copyright:
© 2015 Taylor & Francis.
PY - 2016/3/3
Y1 - 2016/3/3
N2 - Background and Objectives: Posttraumatic stress disorder (PTSD) and Major Depressive Disorder (MDD) are associated with high disease burden. Pathways by which PTSD and MDD contribute to disease burden are not understood. Design: Path analysis was used to examine pathways between PTSD symptoms, MDD symptoms, and disease burden among 251 low-income heart failure patients. Methods: In Model 1, we explored the independent relationship between PTSD and MDD symptoms on disease burden. In Model 2, we examined the association of PTSD symptoms and disease burden on MDD symptoms. We also examined indirect associations of PTSD symptoms on MDD symptoms, mediated by disease burden, and of PTSD symptoms on disease burden mediated by MDD symptoms. Results: Disease burden correlated with PTSD symptoms (r =.41; p <.001) and MDD symptoms (r =.43; p <.001) symptoms. Both models fit the data well and displayed comparable fit. MDD symptoms did not mediate the association of PTSD symptoms with disease burden. Disease burden did mediate the relationship between PTSD symptoms and MDD symptoms. Conclusions: Results support the importance of detection of PTSD in individuals with disease. Results also provide preliminary models for testing longitudinal data in future studies.
AB - Background and Objectives: Posttraumatic stress disorder (PTSD) and Major Depressive Disorder (MDD) are associated with high disease burden. Pathways by which PTSD and MDD contribute to disease burden are not understood. Design: Path analysis was used to examine pathways between PTSD symptoms, MDD symptoms, and disease burden among 251 low-income heart failure patients. Methods: In Model 1, we explored the independent relationship between PTSD and MDD symptoms on disease burden. In Model 2, we examined the association of PTSD symptoms and disease burden on MDD symptoms. We also examined indirect associations of PTSD symptoms on MDD symptoms, mediated by disease burden, and of PTSD symptoms on disease burden mediated by MDD symptoms. Results: Disease burden correlated with PTSD symptoms (r =.41; p <.001) and MDD symptoms (r =.43; p <.001) symptoms. Both models fit the data well and displayed comparable fit. MDD symptoms did not mediate the association of PTSD symptoms with disease burden. Disease burden did mediate the relationship between PTSD symptoms and MDD symptoms. Conclusions: Results support the importance of detection of PTSD in individuals with disease. Results also provide preliminary models for testing longitudinal data in future studies.
KW - chronic disease burden
KW - congestive heart failure
KW - depression
KW - path analysis
KW - posttraumatic stress disorder
UR - http://www.scopus.com/inward/record.url?scp=84955199664&partnerID=8YFLogxK
U2 - 10.1080/10615806.2015.1006206
DO - 10.1080/10615806.2015.1006206
M3 - Article
C2 - 25599115
AN - SCOPUS:84955199664
SN - 1061-5806
VL - 29
SP - 139
EP - 152
JO - Anxiety, Stress and Coping
JF - Anxiety, Stress and Coping
IS - 2
ER -
